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Recombinant Mouse Lipocalin-2/NGAL protein (His Tag)

种属

Mouse

纯度

>90 %, SDS-PAGE

标签

His Tag

生物活性

未测试

Cat no : Eg0572

Print datasheet

Synonyms

NGAL, Lcn2, Lipocalin-2, Lipocalin 2, Neutrophil gelatinase-associated lipocalin

验证数据展示

  • Purity of Recombinant Mouse Lipocalin-2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

    Purity of Recombinant Mouse Lipocalin-2 was determined by SDS-PAGE. The protein was resolved in an SDS-PAGE in reducing (R) and non-reducing (NR) conditions and stained using Coomassie blue.

产品信息

纯度 >90 %, SDS-PAGE
内毒素 <0.1 EU/μg protein, LAL method
生物活性 Not tested
来源 HEK293-derived Mouse Lipocalin-2 protein Gln21-Asn200 (Accession# P11672) with a His tag at the C-terminus.
基因ID 16819
蛋白编号 P11672
预测分子量 22.3 kDa
SDS-PAGE 23-25 kDa, reducing (R) conditions
组分 Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. Normally 5% trehalose and 5% mannitol are added as protectants before lyophilization.
复溶 Briefly centrifuge the tube before opening. Reconstitute at 0.1-0.5 mg/mL in sterile water.
储存条件
It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
  • Until expiry date, -20℃ to -80℃ as lyophilized proteins.
  • 3 months, -20℃ to -80℃ under sterile conditions after reconstitution.
运输条件 The product is shipped at ambient temperature. Upon receipt, store it immediately at the recommended temperature.

背景信息

Neutrophil gelatinase-associated lipocalin (NGAL) also known as Lipocalin-2 (LCN2), is a secreted glycoprotein that belongs to the lipocalin protein family. Several roles of NGAL was identified, including iron trafficking, chemotactic, and promote cell differentiation and proliferation. NGAL was originally found in neutrophils, and expressed in tissues containing renal, uterus, liver, spleen, as well as cardiomyocytes, neurons and immune cells. NGAL is a significant biomarker of cardiovascular diseases, ischemic stroke, acute renal injury, inflammation and metabolic diseases.

参考文献:

1. Bauvois B. et al. (2018). Cancers (Basel). 18;10(9).
2. Buonafine M. et al. (2018). Clin Sci (Lond). 132(9):909-923.
3. Abella V. et al. (2015). Biomarkers. 20(8):565-71.
4. Devarajan P. et al. (2008). Scand J Clin Lab Invest Suppl. 241:89-94.