MultiPro™ 5CFLX Anti-Human CD122/IL-2RB (Polyclonal)
CD122/IL-2RB Polyclonal Antibody for Single Cell (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Single Cell (Intra)
Conjugate
5CFLX
Barcode Sequence
GGTCTGTGACAGCGA
验证数据展示
经过测试的应用
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
推荐稀释比
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
产品信息
G13602-1-5C targets CD122/IL-2RB in Single Cell (Intra) applications and shows reactivity with Human samples.
Tested Applications | Single Cell (Intra) Application Description |
Tested Reactivity | Human |
Immunogen | CD122/IL-2RB fusion protein Ag3929 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Oligo Conjugate |
Type | Polyclonal |
Full Name | MultiPro™ 5CFLX Anti-Human CD122/IL-2RB (Polyclonal) |
Synonyms | CD122, CD122/IL-2RB, IL 2 receptor subunit beta, IL 2R subunit beta, IL 2RB, IL2RB, IL-2RB, interleukin 2 receptor, beta, P70 75, p75 |
Calculated Molecular Weight | 551 aa, 61 kDa |
GenBank Accession Number | BC025691 |
Gene Symbol | IL2RB |
Gene ID (NCBI) | 3560 |
ENSEMBL Gene ID | ENSG00000100385 |
Conjugate | 5CFLX |
Full Oligo Sequence | CGGAGATGTGTATAAGAGACAGGGTCTGTGACAGCGACCCATATAAGAAA |
Barcode Sequence | GGTCTGTGACAGCGA |
Form | Liquid |
UNIPROT ID | P14784 |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C Stable for one year after shipment. |
背景介绍
The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.
Protocols
Our current MultiPro staining protocol for the cocktail | Download protocol |
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdf | Download protocol |