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MultiPro™ 5CFLX Anti-Human LDLR (1A2A3)

LDLR Monoclonal Antibody for Single Cell (Intra)

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

Barcode Sequence

AGCAGGACTAACGAG

CloneNo.

1A2A3

Cat no : G66414-1-5C

Print datasheet

Synonyms

FH, FHC, LDL receptor, LDLR

验证数据展示

  • Single Cell Sequencing experiment G66414-1-5C on Resting PBMC

    Single Cell Sequencing experiment G66414-1-5C on Resting PBMC

    G66414-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

推荐稀释比

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G66414-1-5C targets LDLR in Single Cell (Intra) applications and shows reactivity with Human samples.

Tested Applications Single Cell (Intra) Application Description
Tested Reactivity Human
Immunogen LDLR fusion protein Ag1236 种属同源性预测
Host / Isotype Mouse / IgG1
Class Oligo Conjugate
Type Monoclonal
Full Name MultiPro™ 5CFLX Anti-Human LDLR (1A2A3)
Synonyms FH, FHC, LDL receptor, LDLR
Calculated Molecular Weight 95 kDa
GenBank Accession NumberBC014514
Gene Symbol LDLR
Gene ID (NCBI) 3949
ENSEMBL Gene IDENSG00000130164
Conjugate 5CFLX
Full Oligo SequenceCGGAGATGTGTATAAGAGACAGAGCAGGACTAACGAGCCCATATAAGAAA
Barcode SequenceAGCAGGACTAACGAG
Form Liquid
UNIPROT IDP01130
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C Stable for one year after shipment.

背景介绍

LDLR (low density lipoprotein receptor) is a member of the LDL receptor gene family and is involved in receptor-mediated endocytosis of specific ligands. The LDLR is a cell surface glycoprotein that scavenges LDL from the blood and regulates plasma LDL cholesterol. The cytoplasmic domain of the LDL receptor is necessary for the receptor to cluster in coated pits, which promotes the rapid endocytosis of bound LDL. The protein is highly glycosylated through N- and O-linkages and thus migrates at 100 to 160 kDa bands on SDS-PAGE.

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol