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MultiProTM 5CFLX Anti-Human MAFB (Polyclonal)

MAFB Polyclonal Antibody for Single Cell (Intra)

Host / Isotype

Rabbit / IgG

Reactivity

Human

Applications

Single Cell (Intra)

Conjugate

5CFLX

Barcode Sequence

TCGCGGACCAGGAAT

Cat No : G20189-1-5C

Print datasheet

Synonyms

KRML, Maf B, MAFB, Transcription factor MafB

验证数据展示

  • Single Cell Sequencing experiment G20189-1-5C on Resting PBMC

    Single Cell Sequencing experiment G20189-1-5C on Resting PBMC

    G20189-1-5C was used to stain Resting PBMC and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

  • Single Cell Sequencing experiment G20189-1-5C on PBMC treated with 4hr LPS + TI

    Single Cell Sequencing experiment G20189-1-5C on PBMC treated with 4hr LPS + TI

    G20189-1-5C was used to stain PBMC under 4hr LPS + TI treatment and analyzed with 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing kit with Fix-Stain protocol.

经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.

推荐稀释比

ApplicationDilution
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G20189-1-5C targets MAFB in Single Cell (Intra) applications and shows reactivity with Human samples.

Tested Applications Single Cell (Intra) Application Description
Tested Reactivity Human
Immunogen MAFB fusion protein Ag14102 种属同源性预测
Host / Isotype Rabbit / IgG
Class Oligo Conjugate
Type Polyclonal
Full Name MultiProTM 5CFLX Anti-Human MAFB (Polyclonal)
Synonyms KRML, Maf B, MAFB, Transcription factor MafB
Calculated Molecular Weight 323 aa, 36 kDa
GenBank Accession NumberBC036689
Gene Symbol MAFB
Gene ID (NCBI) 9935
ENSEMBL Gene IDENSG00000204103
Conjugate 5CFLX
Full Oligo SequenceCGGAGATGTGTATAAGAGACAGTCGCGGACCAGGAATCCCATATAAGAAA
Barcode SequenceTCGCGGACCAGGAAT
Form Liquid
UNIPROT IDQ9Y5Q3
Storage Buffer PBS with 1mM EDTA and 0.09% sodium azide
Storage Conditions2-8°C

背景介绍

MAFB (MAF BZIP Transcription Factor B), also known as V-maf musculoaponeurotic fibrosarcoma oncogene homolog B, is a widely expressed basic leucine zipper transcription factor belonging to the Maf family. MAFB expression is significantly elevated in response to a broad range of metabolic and immunological stimuli that promote macrophage M2 polarization, cholesterol efflux, or both, whereas it is strongly down-regulated in response to various pro-inflammatory pathogenic triggers(PMID: 28790455). MAFB is highly expressed in tumor tissues and required for proliferation and tumorigenicity of osteosarcoma cells(PMID: 32234710) and is a marker of tumor-associated macrophages in both mouse and human(PMID: 31679694).

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol