MultiPro® 5CFLX Anti-Human SP1 (4G3H3)

SP1 Monoclonal Antibody for Single Cell (Intra)
Cat No. G66508-1-5C

产品说明书

CloneNo. 4G3H3

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

Single Cell (Intra)

SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  {{ptg:cur_Conjugation}}
规格: 

-/ -


经过测试的应用

Positive Single Cell (Intra) detected in10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Planning an IHC experiment? We recommend our IHCeasy SP1 Ready-To-Use IHC Kit. SP1 primary antibody included.

推荐稀释比

应用推荐稀释比
SINGLE CELL (INTRA)<0.5ug/test
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

产品信息

G66508-1-5C targets SP1 in Single Cell (Intra) applications and shows reactivity with Human samples.

经测试应用 Single Cell (Intra) Application Description
经测试反应性 Human
免疫原 SP1 fusion protein Ag16720 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Oligo Conjugate
产品类型 Monoclonal
全称 MultiPro® 5CFLX Anti-Human SP1 (4G3H3)
别名 SP1, Sp1 transcription factor, Transcription factor Sp1, TSFP1
计算分子量 785 aa, 81 kDa
GenBank蛋白编号BC062539
基因名称 SP1
Gene ID (NCBI) 6667
ENSEMBL Gene IDENSG00000185591
RRIDAB_3673956
偶联类型 5CFLX
完整寡核苷酸序列CGGAGATGTGTATAAGAGACAGTCATTGCGGATTAGCCCCATATAAGAAA
条形码序列TCATTGCGGATTAGC
形式 Liquid
UNIPROT IDP08047
储存缓冲液 PBS with 1mM EDTA and 0.09% sodium azide , pH 7.3
储存条件2-8°C Stable for one year after shipment.

背景介绍

The transcription factor Sp1 is a C2H2 zinc-finger protein that is involved in the regulation of a wide variety of genes, including housekeeping genes and tumor-developing genes. It is associated with tumor development, growth, and metastasis [PMID: 16209919]. It regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Besides, it has a role in modulating the cellular response to DNA damage, recruiting SMARCA4/BRG1 on the c-FOS promoter, regulation of FE65 gene expression [PMID:11371615,16332679]. SP1 has some isoforms with MW ~95-106 kDa and ~60 kDa [PMID:17462816].

Protocols

Our current MultiPro staining protocol for the cocktailDownload protocol
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdfDownload protocol
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