MultiPro® 5CFLX Anti-Human SYK (4C4A12)
SYK Monoclonal Antibody for Single Cell (Intra)
Host / Isotype
Mouse / IgG2b
Reactivity
Human
Applications
Single Cell (Intra)
Conjugate
5CFLX
Barcode Sequence
CGTGATGCGCTGACG
CloneNo.
4C4A12
验证数据展示
经过测试的应用
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
推荐稀释比
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
产品信息
G66721-1-5C targets SYK in Single Cell (Intra) applications and shows reactivity with Human samples.
Tested Applications | Single Cell (Intra) Application Description |
Tested Reactivity | Human |
Immunogen | SYK fusion protein Ag17654 种属同源性预测 |
Host / Isotype | Mouse / IgG2b |
Class | Oligo Conjugate |
Type | Monoclonal |
Full Name | MultiPro® 5CFLX Anti-Human SYK (4C4A12) |
Synonyms | DKFZp313N1010, FLJ25043, FLJ37489, spleen tyrosine kinase, SYK, Tyrosine protein kinase SYK |
Calculated Molecular Weight | 635 aa, 72 kDa |
GenBank Accession Number | BC001645 |
Gene Symbol | SYK |
Gene ID (NCBI) | 6850 |
ENSEMBL Gene ID | ENSG00000165025 |
Conjugate | 5CFLX |
Full Oligo Sequence | CGGAGATGTGTATAAGAGACAGCGTGATGCGCTGACGCCCATATAAGAAA |
Barcode Sequence | CGTGATGCGCTGACG |
Form | Liquid |
UNIPROT ID | P43405 |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C Stable for one year after shipment. |
背景介绍
SYK(spleen tyrosine kinase) is a key regulator of signal transduction events,apoptosis and orderly cell cycle progression in B-lineage lymphoid cells. Although SYK has not been linked to a human disease, defective expression of the closely related T-cell tyrosine kinase ZAP-70 has been associated with severe combined immunodeficiency(PMID:11494125). This protein has 2 isoforms produced by alternative splicing. SYK also promotes liver fibrosis by activation of hepatic stellate cells and acts as a biomarker for human hepatocellular carcinoma. (PMID: 29537660)
Protocols
Our current MultiPro staining protocol for the cocktail | Download protocol |
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdf | Download protocol |