MultiPro™ 5CFLX Anti-Human TCF7 (Polyclonal)
TCF7 Polyclonal Antibody for Single Cell (Intra)
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
Single Cell (Intra)
Conjugate
5CFLX
Barcode Sequence
CGCCTATAGAGACGC
验证数据展示
经过测试的应用
Positive Single Cell (Intra) detected in | 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product. |
Planning an IHC experiment? We recommend our IHCeasy TCF7 Ready-To-Use IHC Kit. TCF7 primary antibody included.
推荐稀释比
Application | Dilution |
---|---|
SINGLE CELL (INTRA) | <0.5ug/test |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. |
产品信息
G14464-1-5C targets TCF7 in Single Cell (Intra) applications and shows reactivity with Human samples.
Tested Applications | Single Cell (Intra) Application Description |
Tested Reactivity | Human |
Immunogen | TCF7 fusion protein Ag5792 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Oligo Conjugate |
Type | Polyclonal |
Full Name | MultiPro™ 5CFLX Anti-Human TCF7 (Polyclonal) |
Synonyms | T cell factor 1, TCF 1, TCF 7, TCF1, TCF7, Transcription factor 7 |
Calculated Molecular Weight | 42 kDa |
GenBank Accession Number | BC048769 |
Gene Symbol | TCF7 |
Gene ID (NCBI) | 6932 |
ENSEMBL Gene ID | ENSG00000081059 |
Conjugate | 5CFLX |
Full Oligo Sequence | CGGAGATGTGTATAAGAGACAGCGCCTATAGAGACGCCCCATATAAGAAA |
Barcode Sequence | CGCCTATAGAGACGC |
Form | Liquid |
UNIPROT ID | P36402 |
Storage Buffer | PBS with 1mM EDTA and 0.09% sodium azide |
Storage Conditions | 2-8°C Stable for one year after shipment. |
背景介绍
TCF7, also known as TCF1, belongs to the TCF/LEF family. TCF7 is part of the Wnt signaling pathway and plays an important role in the differentiation and self-renewal of memory T cells. It has been found that TCF7 is necessary to revive T cells in response to PD-1 blockade against viral infection or cancer. TCF7 is mainly expressed in T-cells and is also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. TCF7 has 16 isoforms with the molecular mass of 28-54 kDa (PMID: 34044317).
Protocols
Our current MultiPro staining protocol for the cocktail | Download protocol |
10x Genomics CG000149_Demonstrated Protocol CellSurface Protein Labeling_Rev D.pdf | Download protocol |