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Host
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Species Reactivity
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Species Reactivity
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Conjugate
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验证数据展示

  • WB analysis of pig heart using 60357-1-Ig (same clone as 60357-1-PBS)

    WB analysis of pig heart using 60357-1-Ig (same clone as 60357-1-PBS)

    pig heart tissue were subjected to SDS PAGE followed by western blot with 60357-1-Ig (Myocilin antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 60357-1-Ig (Myocilin antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 60357-1-Ig (Myocilin antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

Myocilin Monoclonal antibody, PBS Only

Myocilin Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60357-1-PBS

产品说明书

CloneNo. 4B1F6

宿主/亚型

Mouse / IgG2a

种属反应性

human, mouse, pig, rat

应用

WB, IHC, Indirect ELISA

别名

GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60357-1-PBS targets Myocilin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, mouse, pig, rat
免疫原 Myocilin fusion protein Ag5492 种属同源性预测
宿主/亚型 Mouse / IgG2a
抗体类别 Monoclonal
产品类型 Antibody
全称 myocilin, trabecular meshwork inducible glucocorticoid response
别名 GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
计算分子量 57 kDa
观测分子量 50-57 kDa
GenBank蛋白编号BC029261
基因名称 Myocilin
Gene ID (NCBI) 4653
RRIDAB_2881465
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ99972
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893; 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622).