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Myocilin Monoclonal antibody, PBS Only

Myocilin Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, pig, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

4B1F6

Cat No : 60357-1-PBS

Print datasheet

Synonyms

GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR

验证数据展示

  • WB analysis of pig heart using 60357-1-Ig (same clone as 60357-1-PBS)

    WB analysis of pig heart using 60357-1-Ig (same clone as 60357-1-PBS)

    pig heart tissue were subjected to SDS PAGE followed by western blot with 60357-1-Ig (Myocilin antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 60357-1-Ig (Myocilin antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

  • IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    IHC staining of human heart using 60357-1-Ig (same clone as 60357-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human heart tissue slide using 60357-1-Ig (Myocilin antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 60357-1-PBS in a different storage buffer formulation.

产品信息

60357-1-PBS targets Myocilin in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, pig, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, pig, rat
Immunogen Myocilin fusion protein Ag5492 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name myocilin, trabecular meshwork inducible glucocorticoid response
Synonyms GLC1A, GPOA, JOAG, JOAG1, MYOC, myocilin, TIGR
Calculated Molecular Weight 57 kDa
Observed Molecular Weight 50-57 kDa
GenBank Accession NumberBC029261
Gene Symbol Myocilin
Gene ID (NCBI) 4653
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ99972
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Myocilin (MYOC), also known as TIGR or GLC1A, is a secreted glycoprotein of the olfactomedin family, originally identified in trabecular meshwork cells after prolonged treatment with glucocorticoids, and, independently, in the retina (PMID: 9176893; 9169133). It may participate in the obstruction of fluid outflow in the trabecular meshwork. Defects in MYOC are the cause of primary open angle glaucoma (POAG) (PMID: 21709622).