Napsin A Monoclonal antibody

Napsin A Monoclonal Antibody for ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, rat , mouse

Applications

ELISA and More (1)

Conjugate

Unconjugated

CloneNo.

2D12A2

Cat no : 60259-1-Ig

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Synonyms

Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02



Planning an IHC experiment? We recommend our IHCeasy Napsin A Ready-To-Use IHC Kit. Napsin A primary antibody included.
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.

发表文章中的应用

IHCSee 1 publications below

产品信息

60259-1-Ig targets Napsin A in IHC, ELISA applications and shows reactivity with human, rat , mouse samples.

Tested Applications ELISA Application Description
Cited ApplicationsIHC
Tested Reactivity human, rat , mouse
Cited Reactivityhuman
Immunogen Napsin A fusion protein Ag9721 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name napsin A aspartic peptidase
Synonyms Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02
Calculated Molecular Weight 420 aa, 45 kDa
Observed Molecular Weight 45 kDa
GenBank Accession NumberBC017842
Gene Symbol Napsin A
Gene ID (NCBI) 9476
RRIDAB_2881380
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO96009
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).

发表文章

SpeciesApplicationTitle
humanIHC

Oncotarget

Accelerated hepatocellular carcinoma development in CUL4B transgenic mice.

Authors - Jupeng Yuan