验证数据展示
Planning an IHC experiment? We recommend our IHCeasy Napsin A Ready-To-Use IHC Kit. Napsin A primary antibody included.
Planning an IF experiment? We recommend our CoraLite® Plus 488 conjugated versions of this antibody.
发表文章中的应用
| IHC | See 1 publications below |
产品信息
60259-1-Ig targets Napsin A in IHC, ELISA applications and shows reactivity with human, rat , mouse samples.
| 经测试应用 | ELISA Application Description |
| 文献引用应用 | IHC |
| 经测试反应性 | human, rat , mouse |
| 文献引用反应性 | human |
| 免疫原 | Napsin A fusion protein Ag9721 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | napsin A aspartic peptidase |
| 别名 | Asp 4, ASP4, Aspartyl protease 4, KAP, Kdap, NAP1, NAPA, NAPSA, Napsin 1, Napsin A, napsin A aspartic peptidase, Pronapsin A, SNAPA, TA01/TA02 |
| 计算分子量 | 420 aa, 45 kDa |
| 观测分子量 | 45 kDa |
| GenBank蛋白编号 | BC017842 |
| 基因名称 | Napsin A |
| Gene ID (NCBI) | 9476 |
| RRID | AB_2881380 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | O96009 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Napsin is found in two isoforms, napsin A and B, with highly homologous nucleotide sequences (91.2%). Napsin A appears to be a functional proteinase, predominantly expressed in lung and kidney. Napsin B is transcribed exclusively in cells related to the immune system and lacks an in-frame stop codon and is believed to be a pseudogene.(PMID:12698189). Napsin A is superior to TTF-1 in distinguishing primary lung ACA from other carcinomas (except kidney), particularly primary lung small cell carcinoma, and primary thyroid carcinoma.(PMID:22288963).