验证数据展示
经过测试的应用
Positive IHC detected in | human heart tissue, human placenta tissue, human skeletal muscle tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
应用 | 推荐稀释比 |
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Immunohistochemistry (IHC) | IHC : 1:20-1:200 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
产品信息
20807-1-AP targets neuron navigator 1 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IHC, ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | neuron navigator 1 fusion protein Ag14747 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | neuron navigator 1 |
别名 | KIAA1151, KIAA1213, NAV1, neuron navigator 1, POMFIL3, steerin 1, STEERIN1, Unc 53 homolog 1, unc53H1 |
计算分子量 | 1877 aa, 202 kDa |
GenBank蛋白编号 | BC007523 |
基因名称 | NAV1 |
Gene ID (NCBI) | 89796 |
RRID | AB_10732685 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8NEY1 |
储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuron navigator 1 (NAV1) gene encodes a large protein belongs to the Nav/unc-53 family and 7 isoforms of NAV1 are produced by alternative splicing. NAV1 is localized in cytoplasm and expressed at high levels in heart, skeletal muscle and placenta, and especially in neuronal growth cones. Besides its nucleotide binding activity, NAV1 interacts with tubulin and associates with a subset of microtubule plus end, therefore playing a role in neuronal migration.
实验方案
Product Specific Protocols | |
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IHC protocol for neuron navigator 1 antibody 20807-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |