验证数据展示
经过测试的应用
| Positive WB detected in | rat brain tissue, mouse brain tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:2000-1:10000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
84222-2-RR targets NETO2 in WB, ELISA applications and shows reactivity with human, mouse, rat samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse, rat |
| 免疫原 | NETO2 fusion protein Ag2971 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Recombinant |
| 产品类型 | Antibody |
| 全称 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| 别名 | UNQ1926/PRO4401, Neuropilin and tolloid-like protein 2, NEOT2, BTCL2, Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2 |
| 计算分子量 | 525 aa, 59 kDa |
| 观测分子量 | 59 kDa |
| GenBank蛋白编号 | BC012381 |
| 基因名称 | NETO2 |
| Gene ID (NCBI) | 81831 |
| RRID | AB_3671776 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Protein A purification |
| UNIPROT ID | Q8NC67 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuropilin and tolloid-like 2 (NETO2), a member of the subfamily of CUB domain and LDLa-containing proteins, was identified as an auxiliary protein of neuronal kainate receptors (KARs) and played critical roles in regulating the functions of KARs. It was also able to bind to the active oligomeric form of K+-Cl− cotransporter (KCC2) to enhance its recycling in hippocampal neurons. Recently, elevated mRNA levels of NETO2 were detected in several types of tumors.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for NETO2 antibody 84222-2-RR | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |