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NEUROD2 Monoclonal antibody, PBS Only

NEUROD2 Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, mouse, pig

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C7B3

Cat no : 68284-1-PBS

Print datasheet

Synonyms

bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2

验证数据展示

  • WB analysis using 68284-1-Ig (same clone as 68284-1-PBS)

    WB analysis using 68284-1-Ig (same clone as 68284-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse cerebellum using 68284-1-Ig (same clone as 68284-1-PBS)

    WB analysis of mouse cerebellum using 68284-1-Ig (same clone as 68284-1-PBS)

    mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

产品信息

68284-1-PBS targets NEUROD2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, pig samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human, mouse, pig
Immunogen NEUROD2 fusion protein Ag26068 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name neurogenic differentiation 2
Synonyms bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2
Calculated Molecular Weight 41 kDa
Observed Molecular Weight41-50 kDa
GenBank Accession NumberBC022481
Gene Symbol NEUROD2
Gene ID (NCBI) 4761
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ15784
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NEUROD2 (Neurogenic differentiation factor 2), is transcriptional regulator that regulates early neuronal differentiation during development (PMID: 7754368). NeuroD2 is expressed in the postnatal cortex and mediate the activity-dependent refinement of thalamocortical axon terminals (PMID: 17453014). NeuroD2 is mainly involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Mutantions in NEUROD2 can cause neurodevelopmental disorders including intellectual disability and autism spectrum disorders (PMID: 34188164).