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验证数据展示

  • WB analysis using 68284-1-Ig (same clone as 68284-1-PBS)

    WB analysis using 68284-1-Ig (same clone as 68284-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated GAPDH Monoclonal antibody (HRP-60004) as loading control. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

  • WB analysis of mouse cerebellum using 68284-1-Ig (same clone as 68284-1-PBS)

    WB analysis of mouse cerebellum using 68284-1-Ig (same clone as 68284-1-PBS)

    mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 68284-1-Ig (NEUROD2 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68284-1-PBS in a different storage buffer formulation.

NEUROD2 Monoclonal antibody, PBS Only

NEUROD2 Monoclonal Antibody for WB, Indirect ELISA
Cat No. 68284-1-PBS

产品说明书

CloneNo. 2C7B3

宿主/亚型

Mouse / IgG1

种属反应性

Human, mouse, pig

应用

WB, Indirect ELISA

别名

bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2

缓冲液配方:  PBS Only
PBS, Azide, Glycerol
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

68284-1-PBS targets NEUROD2 in WB, Indirect ELISA applications and shows reactivity with Human, mouse, pig samples.

经测试应用 WB, Indirect ELISA Application Description
经测试反应性 Human, mouse, pig
免疫原

CatNo: Ag26068

Product name: Recombinant human NEUROD2 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 314-382 aa of BC022481

Sequence: DSSPDHEKSYHYSMHYSALPGSRPTGHGLVFGSSAVRGGVHSENLLSYDMHLHHDRGPMYEELNAFFHN

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 neurogenic differentiation 2
别名 bHLHa1, NDRF, NeuroD related factor, NEUROD2, neurogenic differentiation 2
计算分子量 41 kDa
观测分子量41-50 kDa
GenBank蛋白编号BC022481
基因名称 NEUROD2
Gene ID (NCBI) 4761
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ15784
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NEUROD2 (Neurogenic differentiation factor 2), is transcriptional regulator that regulates early neuronal differentiation during development (PMID: 7754368). NeuroD2 is expressed in the postnatal cortex and mediate the activity-dependent refinement of thalamocortical axon terminals (PMID: 17453014). NeuroD2 is mainly involved in the development of the cerebellar and hippocampal granular neurons, neurons in the basolateral nucleus of amygdala and the hypothalamic-pituitary axis. Mutantions in NEUROD2 can cause neurodevelopmental disorders including intellectual disability and autism spectrum disorders (PMID: 34188164).

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