验证数据展示
Planning an IHC experiment? We recommend our IHCeasy NHE1/SLC9A1 Ready-To-Use IHC Kit. NHE1/SLC9A1 primary antibody included.
产品信息
67363-1-PBS targets NHE1 in WB, Indirect ELISA applications and shows reactivity with human, rat samples.
| Tested Applications | WB, Indirect ELISA Application Description |
| Tested Reactivity | human, rat |
| Immunogen | NHE1 fusion protein Ag14329 种属同源性预测 |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Full Name | solute carrier family 9 (sodium/hydrogen exchanger), member 1 |
| Synonyms | SLC9A1, Na(+)/H(+) exchanger 1, Na(+)/H(+) antiporter, amiloride-sensitive, FLJ42224, APNH1 |
| Calculated Molecular Weight | 815 aa, 91 kDa |
| Observed Molecular Weight | 110 kDa |
| GenBank Accession Number | BC012121 |
| Gene Symbol | NHE1 |
| Gene ID (NCBI) | 6548 |
| RRID | AB_2882615 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | P19634 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NHE1, also named as SLC9A1, is involved in pH regulation that can eliminate acids generated by active metabolism and counter adverse environmental conditions. NHE1 plays an important role in signal transduction. It has been shown that NHE1 participates in the development and progression of human breast cancer, gastric cancer and others. NHE1 has some isoforms with 91 kDa , 110 kDa (phosphoglycoprotein) and 210 kDa (dimeric protein). (PMID:28098891, 27751915, 8300588)