验证数据展示
产品信息
13921-1-PBS targets NKX2-5 in WB, IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, IF-P, Indirect ELISA Application Description |
Tested Reactivity | human, mouse |
Immunogen | NKX2-5 fusion protein Ag4930 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | NK2 transcription factor related, locus 5 (Drosophila) |
Synonyms | |
Calculated Molecular Weight | 324 aa, 35 kDa |
Observed Molecular Weight | 30-42 kda |
GenBank Accession Number | BC025711 |
Gene Symbol | NKX2-5 |
Gene ID (NCBI) | 1482 |
RRID | AB_1851479 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | P52952 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Homeobox-containing genes play critical roles in regulating tissue-specific gene expression essential for tissue differentiation, as well as determining the temporal and spatial patterns of development [PMID: 7665173]. NKX2-5 encoded by homeobox-containing genes that implicated in commitment to and/or differentiation of the myocardial lineage, and acts as a transcriptional activator of ANF in cooperation with GATA4. During embryonic development, NKX2-5 plays pivotal roles in specifying cardiac progenitors, cardiac morphogenesis, cardiomyocyte differentiation and conduction system development [PMID: 22824467].