neuromedin B Polyclonal antibody
neuromedin B Polyclonal Antibody for IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse and More (2)
Applications
IHC, ELISA and More (1)
Conjugate
Unconjugated
验证数据展示
经过测试的应用
| Positive IHC detected in | mouse brain tissue, human brain tissue, human breast cancer tissue, human skin tissue, human stomach tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
| Application | Dilution |
|---|---|
| Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
发表文章中的应用
| WB | See 1 publications below |
| IHC | See 2 publications below |
产品信息
10888-1-AP targets neuromedin B in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
| Tested Applications | IHC, ELISA Application Description |
| Cited Applications | WB, IHC |
| Tested Reactivity | human, mouse |
| Cited Reactivity | human, monkey, chimpanzee |
| Immunogen | neuromedin B fusion protein Ag0842 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Full Name | neuromedin B |
| Synonyms | neuromedin B, NMB |
| Calculated Molecular Weight | 16 kDa |
| GenBank Accession Number | BC007407 |
| Gene Symbol | NMB |
| Gene ID (NCBI) | 4828 |
| RRID | AB_10895967 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Antigen affinity purification |
| UNIPROT ID | P08949 |
| Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
| Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Neuromedin B (NMB) is a bombesin-like peptide, which inhibits food intake and modulates stress-related behaviour. It exerts its function via NMB receptor (NMB-R). NMB is encoded in a 76-amino acid precursor. The mature NMB was reported to be a 10-amino-acid peptide, giving two bands of 1.2 kDa and 1.5 kDa in western blotting. NMB is expressed in brain, gastrointestinal tract, pancreas, adrenals, and adipose tissue. It regulates exocrine and endocrine secretions, cell growth, body temperature and blood pressure and glucose level in vivo.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for neuromedin B antibody 10888-1-AP | Download protocol |
| IHC protocol for neuromedin B antibody 10888-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
发表文章
| Species | Application | Title |
|---|---|---|
Brain Struct Funct The von Economo neurons in frontoinsular and anterior cingulate cortex in great apes and humans. | ||
Cancer Lett Neuromedin B receptor antagonist suppresses tumor angiogenesis and tumor growth in vitro and in vivo. | ||
