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NPHP5/IQCB1 Monoclonal antibody, PBS Only

NPHP5/IQCB1 Monoclonal Antibody for WB,Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

Human

Applications

WB,Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2A9F4

Cat No : 68404-1-PBS

Print datasheet

Synonyms

IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, PIQ, SLSN5

验证数据展示

  • WB analysis using 68404-1-Ig (same clone as 68404-1-PBS)

    WB analysis using 68404-1-Ig (same clone as 68404-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68404-1-Ig (NPHP5,IQCB1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68404-1-PBS in a different storage buffer formulation.

产品信息

68404-1-PBS targets NPHP5/IQCB1 in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB,Indirect ELISA Application Description
Tested Reactivity Human
Immunogen NPHP5/IQCB1 fusion protein Ag8203 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name IQ motif containing B1
Synonyms IQ motif containing B1, IQCB1, KIAA0036, Nephrocystin 5, PIQ, SLSN5
Calculated Molecular Weight 598 aa, 69 kDa
Observed Molecular Weight69 kDa
GenBank Accession NumberBC005806
Gene Symbol IQCB1
Gene ID (NCBI) 9657
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ15051
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

IQCB1, also known as NPHP5, is a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. It has a central coiled-coil region and two calmodulin-binding IQ domains. Localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells, IQCB1 is thought to play a role in ciliary function. Mutations in this gene result in Senior-Loken syndrome type 5, a juvenile disorder characterized by defects in the waste filtering system of the kidney, as well as retinal degradation.