验证数据展示
产品信息
10157-1-PBS targets NPRL2 in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse samples.
经测试应用 | WB, IHC, IP, Indirect ELISA Application Description |
经测试反应性 | human, mouse |
免疫原 | NPRL2 fusion protein Ag0210 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | tumor suppressor candidate 4 |
别名 | |
计算分子量 | 44 kDa |
观测分子量 | 44-50 kDa |
GenBank蛋白编号 | BC002791 |
基因名称 | TUSC4 |
Gene ID (NCBI) | 10641 |
RRID | AB_514025 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q8WTW4 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NPRL2 (NPR2 Like, GATOR1 Complex Subunit) is a Protein Coding gene associated with Epilepsy, Familial Focal. As a component of the GATOR1 complex functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway. Homologous to yeast nitrogen permease (candidate tumor suppressor) (NM_006545, BC021984) gene encodes a protein of molecular mass of 50 kDa. Data by using overlapping and nested homozygous deletions methods indicate that this protein might be a tumor suppressor involved in the development of lung cancers.