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NR1H3 Monoclonal antibody, PBS Only

NR1H3 Monoclonal Antibody for WB,Indirect ELISA,IF

Host / Isotype

Mouse / IgG1

Reactivity

human, rat, pig

Applications

WB,Indirect ELISA,IF

Conjugate

Unconjugated

CloneNo.

4A4F7

Cat No : 60134-1-PBS

Print datasheet

Synonyms

Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1

验证数据展示

  • WB analysis using 60134-1-Ig (same clone as 60134-1-PBS)

    WB analysis using 60134-1-Ig (same clone as 60134-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60134-1-Ig (NR1H3 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

  • IF Staining of HepG2 using 60134-1-Ig (same clone as 60134-1-PBS)

    IF Staining of HepG2 using 60134-1-Ig (same clone as 60134-1-PBS)

    Immunofluorescent analysis of HepG2 cells using 60134-1-Ig (NR1H3 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Mouse IgG (H+L). This data was developed using the same antibody clone with 60134-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy NR1H3 Ready-To-Use IHC Kit. NR1H3 primary antibody included.

产品信息

60134-1-PBS targets NR1H3 in WB, IF, Indirect ELISA applications and shows reactivity with human, rat, pig samples.

Tested Applications WB,Indirect ELISA,IF Application Description
Tested Reactivity human, rat, pig
Immunogen NR1H3 fusion protein Ag6184 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name nuclear receptor subfamily 1, group H, member 3
Synonyms Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1
Calculated Molecular Weight 50 kDa
Observed Molecular Weight 44 kDa
GenBank Accession NumberBC041172
Gene Symbol NR1H3
Gene ID (NCBI) 10062
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ13133
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.

背景介绍

NR1H3, also known as LXRA, is a liver X receptors, which form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. It's also a ligand-activated LXRs and forms heterodimers with retinoid X receptor, then participates in regulating expression of target genes containing LXR response elements.