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验证数据展示

  • IF Staining of photoreceptor progenitor cells using 14246-1-AP (same clone as 14246-1-PBS)

    IF Staining of photoreceptor progenitor cells using 14246-1-AP (same clone as 14246-1-PBS)

    IF result of NR2E3 antibody (14246-1-AP, 1:50) with human photoreceptor progenitors cells. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • WB analysis using 14246-1-AP (same clone as 14246-1-PBS)

    WB analysis using 14246-1-AP (same clone as 14246-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

NR2E3 Polyclonal antibody, PBS Only

NR2E3 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 14246-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat, pig

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

14246-1-PBS targets NR2E3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, rat, pig
免疫原 NR2E3 fusion protein Ag5503 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 nuclear receptor subfamily 2, group E, member 3
别名
计算分子量 45 kDa
观测分子量 43-45 kDa
GenBank蛋白编号BC041421
基因名称 NR2E3
Gene ID (NCBI) 10002
RRIDAB_2155476
偶联类型 Unconjugated
形式 Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9Y5X4
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]