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  • Featured Product
  • KD/KO Validated

NR2E3 Polyclonal antibody, PBS Only

NR2E3 Polyclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat, pig

Applications

WB, IHC, IF/ICC, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14246-1-PBS

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Synonyms

验证数据展示

  • IF Staining of photoreceptor progenitor cells using 14246-1-AP (same clone as 14246-1-PBS)

    IF Staining of photoreceptor progenitor cells using 14246-1-AP (same clone as 14246-1-PBS)

    IF result of NR2E3 antibody (14246-1-AP, 1:50) with human photoreceptor progenitors cells. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • WB analysis using 14246-1-AP (same clone as 14246-1-PBS)

    WB analysis using 14246-1-AP (same clone as 14246-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14246-1-AP (NR2E3 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    IHC staining of human prostate cancer using 14246-1-AP (same clone as 14246-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer using 14246-1-AP (NR2E3 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 14246-1-PBS in a different storage buffer formulation.

产品信息

14246-1-PBS targets NR2E3 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, IHC, IF/ICC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen NR2E3 fusion protein Ag5503 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name nuclear receptor subfamily 2, group E, member 3
Synonyms
Calculated Molecular Weight 45 kDa
Observed Molecular Weight 43-45 kDa
GenBank Accession NumberBC041421
Gene Symbol NR2E3
Gene ID (NCBI) 10002
RRIDAB_2155476
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9Y5X4
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NR2E3, also known as PNR, encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. NR2E3 influences the development of photoreceptors and their differentiation into rod and cone types, and acts as a ranscriptional factor that is an activator of rod development and repressor of cone development [PMID:20725840]. It binds the promoter region of a number of rod- and cone-specific genes, including rhodopsin, M- and S-opsin and rod-specific phosphodiesterase beta subunit. [PMID:15689355]