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验证数据展示

  • WB analysis of HeLa using 60117-2-Ig (same clone as 60117-2-PBS)

    WB analysis of HeLa using 60117-2-Ig (same clone as 60117-2-PBS)

    WB result of NR2F6 antibody (60117-2-Ig, 1:1000) with si-Control and si-NR2F6 transfected HeLa cells. This data was developed using the same antibody clone with 60117-2-PBS in a different storage buffer formulation.

  • IHC staining of human ovary tumor using 60117-2-Ig (same clone as 60117-2-PBS)

    IHC staining of human ovary tumor using 60117-2-Ig (same clone as 60117-2-PBS)

    Immunohistochemical analysis of paraffin-embedded human ovary tumor tissue slide using 60117-2-Ig (NR2F6 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60117-2-PBS in a different storage buffer formulation.

  • WB analysis using 60117-2-Ig (same clone as 60117-2-PBS)

    WB analysis using 60117-2-Ig (same clone as 60117-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60117-2-Ig (NR2F6 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60117-2-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

NR2F6 Monoclonal antibody, PBS Only

NR2F6 Monoclonal Antibody for WB, IHC, Indirect ELISA
Cat No. 60117-2-PBS

产品说明书

CloneNo. 2H2B8

宿主/亚型

Mouse / IgG1

种属反应性

human, rat

应用

WB, IHC, Indirect ELISA

别名

2H2B8, EAR 2, EAR2, EAR-2, ERBAL2

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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产品信息

60117-2-PBS targets NR2F6 in WB, IHC, Indirect ELISA applications and shows reactivity with human, rat samples.

经测试应用 WB, IHC, Indirect ELISA Application Description
经测试反应性 human, rat
免疫原 NR2F6 fusion protein Ag7614 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 nuclear receptor subfamily 2, group F, member 6
别名 2H2B8, EAR 2, EAR2, EAR-2, ERBAL2
计算分子量 43 kDa
观测分子量 43 kDa
GenBank蛋白编号BC002669
基因名称 NR2F6
Gene ID (NCBI) 2063
RRIDAB_2155653
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP10588
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NR2F6 belongs to NR2F subfamily members, which have their roles in the regulation of neurogenesis, organogenesis, and cellular differentiation during embryonic development (PMID:15875024). NR2F6 acts as transcription factor by binding to a TGACCT direct-repeat motif and has been established in controlling facets of central nervous system (CNS) (PMID: 12690040). It is a nuclear attenuator that directly interferes with DNA binding of NF-AT and, subsequently, transcriptional activity of the NF-AT-dependent IL-17 expression. Otherwise, NR2F6 negatively interfered with transcriptional cytokine responses and acted as a barrier against autoimmunity (PMID:18701084).