NRF1 antibody (pAb)
Host / Isotype
Rabbit / IgG
Reactivity
Human, Mouse
Applications
WB
Cat No : 61673,61674 61673
Synonyms
验证数据展示
产品信息
Tested Applications |
WB
Applications Validated by Active Motif: WB: 1:500 - 1:1,500 dilution The addition of 0.05% Tween 20 in the blocking buffer and primary antibody incubation buffer is recommended to aid in detection by Western blot. Individual optimization may be required. |
Tested Reactivity | Human, Mouse |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Immunogen | This antibody was raised against a peptide within the C-terminal region of human NRF1. |
Full Name | NRF1 antibody (pAb) |
Synonyms | NRF1, Nuclear Respiratory Factor 1, Alpha Palindromic-Binding Protein, NRF-1, ALPHA-PAL, Alpha-pal, transcription, transcriptional activator, activator EIF2-alpha, respiration, heme biosynthesis, mitochondrial DNA transcription, antibody, antibodies, polyclonal, pab, western blotting, wb, sample |
Molecular weight | 68 kDa |
GenBank accession number | NP_001280092 | RRID | AB_2793729 | Purification Method | Affinity Purified |
Buffer | Purified IgG in PBS with 30% glycerol and 0.035% sodium azide. Sodium azide is highly toxic. |
Storage | Some products may be shipped at room temperature. This will not affect their stability or performance. Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage. |
背景介绍
NRF1 (Nuclear Respiratory Factor 1) is a transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication.