NSUN2 Recombinant antibody, PBS Only
NSUN2 Uni-rAbTM Recombinant Antibody for IF/ICC, Indirect ELISA
Host / Isotype
Rabbit / IgG
Reactivity
Human
Applications
IF/ICC, Indirect ELISA
Conjugate
Unconjugated
CloneNo.
230186B7
验证数据展示
Planning an IHC experiment? We recommend our IHCeasy NSUN2 Ready-To-Use IHC Kit. NSUN2 primary antibody included.
产品信息
82894-3-PBS targets NSUN2 in IF/ICC, Indirect ELISA applications and shows reactivity with Human samples.
| Tested Applications | IF/ICC, Indirect ELISA Application Description |
| Tested Reactivity | Human |
| Immunogen | NSUN2 fusion protein Ag14791 种属同源性预测 |
| Host / Isotype | Rabbit / IgG |
| Class | Recombinant |
| Type | Antibody |
| Full Name | NOL1/NOP2/Sun domain family, member 2 |
| Synonyms | RNA cytosine C(5)-methyltransferase NSUN2, Myc-induced SUN domain-containing protein, mRNA cytosine C(5)-methyltransferase, EC:2.1.1.-, EC:2.1.1.203, EC:2.1.1.- |
| Calculated Molecular Weight | 767 aa, 86 kDa |
| GenBank Accession Number | BC001041 |
| Gene Symbol | NSUN2 |
| Gene ID (NCBI) | 54888 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification Method | Protein A purification |
| UNIPROT ID | Q08J23 |
| Storage Buffer | PBS Only |
| Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NSUN2, also known as SAKI or Misu (Myc-induced SUN-domain-containing protein), is a methyltransferase which catalyses (cytosine-5-)-methylation of tRNA. NSUN2 is direct target gene of c-Myc and may act downstream of Myc to regulate epidermal cell growth and proliferation. NSUN2 is overexpressed in various cancer tissues and may be a valuable target for cancer therapy and a cancer diagnostic marker. Recently a splicing mutation in NSUN2 has been identified as the cause of a Dubowitz-like syndrome, an autosomal recessive disorder.