验证数据展示
产品信息
83917-5-PBS targets NUCB2/nesfatin-1 in IF/ICC, FC (Intra), Indirect ELISA applications and shows reactivity with human samples.
经测试应用 | IF/ICC, FC (Intra), Indirect ELISA Application Description |
经测试反应性 | human |
免疫原 | NUCB2/nesfatin-1 fusion protein Ag25152 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Recombinant |
产品类型 | Antibody |
全称 | nucleobindin 2 |
别名 | NUCB2, 241037C1, DNA binding protein NEFA, Gastric cancer antigen Zg4, NEFA |
计算分子量 | 50 kDa |
GenBank蛋白编号 | NM_005013 |
基因名称 | NUCB2 |
Gene ID (NCBI) | 4925 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein A purfication |
UNIPROT ID | P80303 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
NucB2, an anorexigenic molecule, is expressed mainly in the hypothalamus, particularly in the supraoptic nucleus (SON) and the paraventricular nucleus (PVN). NucB2 is also expressed in the subfornical organ (SFO). Because the SON and PVN are involved in body fluid regulation, NucB2 may be involved in dehydration-induced anorexia. NUCB2 is composed of a signal peptide of 24 amino acids in the N-terminal region and a protin structure containing 396 amino acids. Nesfatin-1 is an 82-amino-acid peptide hormone cleaved from nucleobindin2 (NUCB2).