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NUP153 Polyclonal antibody, PBS Only

NUP153 Polyclonal Antibody for WB, IP, Indirect ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, IP, Indirect ELISA

Conjugate

Unconjugated

Cat no : 14189-1-PBS

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Synonyms

验证数据展示

  • WB analysis of K-562 using 14189-1-AP (same clone as 14189-1-PBS)

    WB analysis of K-562 using 14189-1-AP (same clone as 14189-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 14189-1-AP (NUP153 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14189-1-PBS in a different storage buffer formulation.

  • IP experiment of K-562 using 14189-1-AP (same clone as 14189-1-PBS)

    IP experiment of K-562 using 14189-1-AP (same clone as 14189-1-PBS)

    IP result of anti-NUP153 (IP:14189-1-AP, 4ug; Detection:14189-1-AP 1:500) with K-562 cells lysate 3600ug. This data was developed using the same antibody clone with 14189-1-PBS in a different storage buffer formulation.

  • WB analysis using 14189-1-AP (same clone as 14189-1-PBS)

    WB analysis using 14189-1-AP (same clone as 14189-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14189-1-AP (NUP153 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14189-1-PBS in a different storage buffer formulation.

产品信息

14189-1-PBS targets NUP153 in WB, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IP, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen NUP153 fusion protein Ag5519 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name nucleoporin 153kDa
Synonyms
Calculated Molecular Weight 154 kDa
Observed Molecular Weight 154 kDa
GenBank Accession NumberBC052965
Gene Symbol NUP153
Gene ID (NCBI) 9972
RRIDAB_2154463
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP49790
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NUP153 is an FG-repeat containing NUP, contains a high-affinity site for importin-β, localizes on the nucleoplasmic face of the nuclear pore and is required for assembly of the nuclear basket and import of a subset of nuclear proteins [PMID:18845677]. NUP153 also facilitates nuclear export of mRNA and ribonucleoprotein particles and may have additional functions within the nucleus [PMID:16195343]. The 53BP1-NUP153/importin-β pathway as an important aspect of the DDR network add to an emerging evidence of subcellular trafficking as an integral part of genome surveillance [PMID:22075984].