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NUP62 Monoclonal antibody, PBS Only

NUP62 Monoclonal Antibody for WB, IHC, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat

Applications

WB, IHC, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2G12B3

Cat no : 66573-1-PBS

Print datasheet

Synonyms

Nucleoporin Nup62, nucleoporin 62kDa, Nuclear pore glycoprotein p62, IBSN, 62 kDa nucleoporin

验证数据展示

  • WB analysis using 66573-1-Ig (same clone as 66573-1-PBS)

    WB analysis using 66573-1-Ig (same clone as 66573-1-PBS)

    Various cells were subjected to SDS PAGE followed by western blot with 66573-1-Ig (NUP62 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66573-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 66573-1-Ig (same clone as 66573-1-PBS)

    IHC staining of human prostate cancer using 66573-1-Ig (same clone as 66573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66573-1-Ig (NUP62 antibody) at dilution of 1:2000 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66573-1-PBS in a different storage buffer formulation.

  • IHC staining of human prostate cancer using 66573-1-Ig (same clone as 66573-1-PBS)

    IHC staining of human prostate cancer using 66573-1-Ig (same clone as 66573-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 66573-1-Ig (NUP62 antibody) at dilution of 1:2000 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66573-1-PBS in a different storage buffer formulation.

产品信息

66573-1-PBS targets NUP62 in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, IHC, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen NUP62 fusion protein Ag4912 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name nucleoporin 62kDa
Synonyms Nucleoporin Nup62, nucleoporin 62kDa, Nuclear pore glycoprotein p62, IBSN, 62 kDa nucleoporin
Calculated Molecular Weight 522 aa, 53 kDa
Observed Molecular Weight 62 kDa
GenBank Accession NumberBC014842
Gene Symbol NUP62
Gene ID (NCBI) 23636
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDP37198
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

NUP62 belongs to the nucleoporin NSP1/NUP62 family. It is essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is probably involved in protein-protein interaction via coiled-coil formation and may function in anchorage of p62 to the pore complex. Defects in NUP62 are the cause of infantile striatonigral degeneration (SNDI). NUP62 consists of a single promoter with a CpG island and three transcribed exons. It is ubiquitously expressed, an observation compatible with its essential role in transporting cargo across the nuclear envelope. (PMID:16029492)