Nemolizumab

Nemolizumab (CIM331) 是一种人源化的抗人白细胞介素-31 受体 a 单克隆抗体,对白细胞介素-31 (IL-31) 与其受体的结合和随后的信号转导有抑制作用。Nemolizumab 可用于研究特应性皮炎伴瘙痒。

CAS号

1476039-58-3

分子式

主要靶点

Interleukin

仅限科研使用

Cat No : CM20205

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Synonyms

CIM331



产品信息

Nemolizumab (CIM331) is a humanized monoclonal antibody against human interleukin-31 receptor A that inhibits the binding and subsequent signal transduction of interleukin-31 (IL-31) to its receptor. Nemolizumab can be used to study atopic dermatitis with pruritus.

CAS号 1476039-58-3
分子式
主要靶点 Interleukin
主要通路 免疫与炎症
分子量
纯度 , 此纯度可做参考,具体纯度与批次有关系,可咨询客服
储存条件
别名 CIM331

参考文献

1.Nakahara T, et, al. Nemolizumab and Atopic Dermatitis: the Interaction Between Interleukin-31 and Interleukin-31 Receptor as a Potential Therapeutic Target for Pruritus in Patients With Atopic Dermatitis. 2018;5:405–14.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2