验证数据展示
产品信息
12833-1-PBS targets Neuropeptide Y in IHC, IF-P, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | IHC, IF-P, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | Neuropeptide Y fusion protein Ag3568 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | neuropeptide Y |
别名 | |
计算分子量 | 97 aa, 11 kDa |
GenBank蛋白编号 | BC029497 |
基因名称 | Neuropeptide Y |
Gene ID (NCBI) | 4852 |
RRID | AB_10791890 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | P01303 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Neuropeptide Y (NPY) is one of the most abundant peptides in the mammalian central nervous system (CNS). NPY has been linked to several physiological and pathological functions, such as feeding behaviour, memory processing, pain, anxiety, cell proliferation and many other processes in the central and peripheral nervous systems. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. In addition, NPY was suggested as a potential neuroprotective agent in Alzheimer's disease by counteracting the toxic effect of β-amyloid in an in vitro model.