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Nicardipine

Nicardipine (Cardene) 是一种二氢吡啶类钙通道阻滞剂，可阻断心脏钙通道，IC50为 1 μM，可用于治疗心绞痛和高血压。

CAS号

55985-32-5

分子式

C26H29N3O6

主要靶点

Calcium Channel

仅限科研使用

Cat No : CM03242

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Synonyms

尼卡地平|Dagan|Antagonil|Cardene|Flusemide

验证数据展示

  • CAS No.: 55985-32-5

    Nicardipine
    CAS#: 55985-32-5

产品信息

Nicardipine hydrochloride, a calcium channel blockers belonging to the dihydropyridine class, is a drug used to treat angina and high blood pressure.

CAS号 55985-32-5
分子式 C26H29N3O6
主要靶点 Calcium Channel
主要通路 离子通道|代谢
分子量 479.53
纯度 99.56%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 尼卡地平|Dagan|Antagonil|Cardene|Flusemide

靶点活性

cardiac calcium channels:1 μM (IC50)

溶解度

DMSO:60 mg/ml (125.12 mM),H2O:Insoluble

参考文献

1.R Stamatiou, et al. The dihydropyridine calcium antagonist nicardipine reduces aortic smooth muscle cell viability, proliferation and migration. Cardiovascular Research, 2018 Apr,114(1):S43.
2.Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1(6):413-31.
3.Sherrin H. Baky. Nic ardipine Hydrochloride.

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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C1   V1   C2   V2