OMA1 Monoclonal antibody

OMA1 Monoclonal Antibody for WB, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human, Mouse and More (1)

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

1H4D12

Cat no : 67449-1-Ig

Print datasheet

Synonyms

2010001O09Rik, DAB1, FLJ33782, MPRP 1, MPRP1, OMA1, YKR087C, ZMPOMA1



经过测试的应用

Positive WB detected inNIH/3T3 cells, HeLa cells, Jurkat cells, LNCaP cells, HEK-293 cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:1000-1:5000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

发表文章中的应用

WBSee 1 publications below

产品信息

67449-1-Ig targets OMA1 in WB, ELISA applications and shows reactivity with Human, Mouse samples.

Tested Applications WB, ELISA Application Description
Cited ApplicationsWB
Tested Reactivity Human, Mouse
Cited Reactivityhuman
Immunogen OMA1 fusion protein Ag11201 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
Synonyms 2010001O09Rik, DAB1, FLJ33782, MPRP 1, MPRP1, OMA1, YKR087C, ZMPOMA1
Calculated Molecular Weight 524 aa, 60 kDa
Observed Molecular Weight 60 kDa
GenBank Accession NumberBC012915
Gene Symbol OMA1
Gene ID (NCBI) 115209
RRIDAB_2882683
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDQ96E52
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Aliquoting is unnecessary for -20oC storage.

背景介绍

OMA1(Overlapping with the m-AAA protease 1 homolog) is also named as MPRP1(Metalloprotease-related protein 1) and belongs to the peptidase M48 family.It is a zinc metalloprotease that spans the inner mitochondrial membrane with a number of predicted membrane spanning domains and the 60 kDa form of OMA1 rapidly accumulated concomitantly with the cleavage of all OPA1 variants,and the 40 kDa form of OMA1 may be the inactive form, with the 60 kDa form being the active enzyme(PMID:20334834)

实验方案

Product Specific Protocols
WB protocol for OMA1 antibody 67449-1-IgDownload protocol
Standard Protocols
Click here to view our Standard Protocols

发表文章

SpeciesApplicationTitle
humanWB

Methods Enzymol

Monitoring retro-translocation of proteins from the mitochondrial intermembrane space

Authors - Magda Krakowczyk