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OPN4 Polyclonal antibody

OPN4 Polyclonal Antibody for IF-P, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse

Applications

IF-P, ELISA

Conjugate

Unconjugated

Cat no : 24478-1-AP

Print datasheet

Synonyms

Opsin-4, opsin 4, MOP, Melanopsin

验证数据展示

  • IF Staining of mouse eye using 24478-1-AP

    IF Staining of mouse eye using 24478-1-AP

    Immunofluorescent analysis of (4% PFA) fixed mouse eye tissue using OPN4 antibody (24478-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L).

经过测试的应用

Positive IF-P detected inmouse eye tissue

推荐稀释比

ApplicationDilution
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

24478-1-AP targets OPN4 in IF-P, ELISA applications and shows reactivity with human, mouse samples.

Tested Applications IF-P, ELISA Application Description
Tested Reactivity human, mouse
Immunogen OPN4 fusion protein Ag21643 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name opsin 4
Synonyms Opsin-4, opsin 4, MOP, Melanopsin
Calculated Molecular Weight 478 aa, 53 kDa
GenBank Accession NumberBC113558
Gene Symbol OPN4
Gene ID (NCBI) 94233
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UHM6
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

OPN4, an opsin that was first isolated from the skin of Xenopus laevis in 1998, belongs not to the vertebrate-type opsin family but rather to the invertebrate-type opsins, which are part of the seven-transmembrane G protein-coupled receptor (GPCR) family (PMID:31989708). In humans, OPN4 is expressed in the retinal ganglion cells in addition to part of the brain (PMID:10632589). Moreover, Opn4 functions as a photoreceptor by detecting brightness levels and discriminating visual signals (PMID:22633808). Opn4 also facilitates visual circuits to acquire optimal settings and light adaptation by measuring irradiance levels (PMID:25517373).

实验方案

Product Specific Protocols
IF protocol for OPN4 antibody 24478-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols