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OPRM1 Polyclonal antibody

OPRM1 Polyclonal Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

WB, ELISA

Conjugate

Unconjugated

Cat no : 28887-1-AP

Print datasheet

Synonyms

MOR, MOP, M OR 1, LMOR, KIAA0403

验证数据展示

  • WB analysis using 28887-1-AP

    WB analysis using 28887-1-AP

    SK-N-SH cells were subjected to SDS PAGE followed by western blot with 28887-1-AP (OPRM1 antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours.

经过测试的应用

Positive WB detected inSK-N-SH cells

推荐稀释比

ApplicationDilution
Western Blot (WB)WB : 1:500-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

28887-1-AP targets OPRM1 in WB, ELISA applications and shows reactivity with human samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human
Immunogen OPRM1 fusion protein Ag30275 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name opioid receptor, mu 1
Synonyms MOR, MOP, M OR 1, LMOR, KIAA0403
Calculated Molecular Weight 45 kDa
Observed Molecular Weight70 kDa
GenBank Accession NumberBC074927
Gene Symbol OPRM1
Gene ID (NCBI) 4988
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDP35372
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

OPRM1 (also known as Mu opioid receptor, MOR1, MOP) is a G protein-coupled receptor that mediates the physiological effects of endogenous opioids as well as the structurally distinct opioid alkaloids including morphine and etorphine (PMID: 9618555). Mu opioid receptor modulates a wide range of physiological functions, particularly involved in the control of pain perception and reward properties (PMID: 30483121). Mu opioid receptor is the principal target of opioid drugs. It is encoded by OPRM1 gene and multiple transcript variants encoding different isoforms have been found. Mu opioid receptor contains sites for N-linked glycosylation. The transcript variants and variations of glycosylation may result in migrating bands of Mu opioid receptor (PMID: 21886594; 11359768).

实验方案

Product Specific Protocols
WB protocol for OPRM1 antibody 28887-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols