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  • Featured Product
  • KD/KO Validated

OTUD7B Monoclonal antibody, PBS Only

OTUD7B Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2b

Reactivity

human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2C12D9

Cat no : 66276-1-PBS

Print datasheet

Synonyms

CEZANNE, OTU domain containing 7B, OTUD7B, ZA20D1, Zinc finger protein Cezanne

验证数据展示

  • WB analysis of Jurkat using 66276-1-Ig (same clone as 66276-1-PBS)

    WB analysis of Jurkat using 66276-1-Ig (same clone as 66276-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 66276-1-Ig (OTUD7B Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66276-1-PBS in a different storage buffer formulation.

产品信息

66276-1-PBS targets OTUD7B in WB, Indirect ELISA applications and shows reactivity with human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human
Immunogen OTUD7B fusion protein Ag10513 种属同源性预测
Host / Isotype Mouse / IgG2b
Class Monoclonal
Type Antibody
Full Name OTU domain containing 7B
Synonyms CEZANNE, OTU domain containing 7B, OTUD7B, ZA20D1, Zinc finger protein Cezanne
Calculated Molecular Weight427aa,48 kDa; 843aa,93 kDa
Observed Molecular Weight 92 kDa
GenBank Accession NumberBC020622
Gene Symbol OTUD7B
Gene ID (NCBI) 56957
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDQ6GQQ9
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

OUTD7B is a member of the A20 family of the deubiquitinating cysteine proteases, which has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. It plays a key role in the negative feedback regulation of NF-κB signaling in response to multiple stimuli and has been described as central gatekeeper in inflammation and immunity.