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Ozenoxacin

Ozenoxacin (T-3912) 是一种非氟喹诺酮抗菌剂，对大多数从在皮肤和软组织感染中分离的微生物有活性。

CAS号

245765-41-7

分子式

C21H21N3O3

主要靶点

Antibacterial

仅限科研使用

Cat No : CM02863

Print datasheet

Synonyms

奥泽沙星|T-3912

验证数据展示

  • CAS No.: 245765-41-7

    Ozenoxacin
    CAS#: 245765-41-7

产品信息

Ozenoxacin（T-3912）is a novel quinolone-class antibiotic that exhibits activity against the majority of microorganisms isolated from skin and soft tissue infections.

CAS号 245765-41-7
分子式 C21H21N3O3
主要靶点 Antibacterial
主要通路 微生物学
分子量 363.41
纯度 99.56%， 此纯度可做参考，具体纯度与批次有关系，可咨询客服
储存条件 Powder: -20°C for 3 years | In solvent: -80°C for 1 year
别名 奥泽沙星|T-3912

体外活性

Ozenoxacin shows potent antibacterial activities against clinical isolates of Gram-positive microorganisms (MICs: 0.008 to 4 mg/L). Ozenoxacin shows good activities against strains of MRSA, MSSA, MSSE, and MRSE with 2, 3, or 4 mutations in the gyrA and grlA (parC) genes [1]. Ozenoxacin inhibits MSSA strains and S. agalactiae strains, with the rates of resistance of >10?10 and 5.3?×?10?10, respectively. The maximum MIC value for mutant strains is 8 mg/L for Ozenoxacin [2].

溶解度

DMSO:5 mg/mL (13.76 mM),Sonification/heating is recommended.

参考文献

1.López Y, et al. In vitro activity of Ozenoxacin against quinolone-susceptible and quinolone-resistant gram-positive bacteria. Antimicrob Agents Chemother. 2013 Dec;57(12):6389-92.
2.López Y, et al. In vitro selection of mutants resistant to ozenoxacin compared with levofloxacin and ciprofloxacin in Gram-positive cocci. J Antimicrob Chemother. 2015 Jan;70(1):57-61

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
×
=
×
C1   V1   C2   V2