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验证数据展示

  • WB analysis of human peripheral blood platelets using 66261-1-Ig (same clone as 66261-1-PBS)

    WB analysis of human peripheral blood platelets using 66261-1-Ig (same clone as 66261-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 66261-1-Ig (PAI-1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66261-1-PBS in a different storage buffer formulation.

  • IHC staining of human kidney using 66261-1-Ig (same clone as 66261-1-PBS)

    IHC staining of human kidney using 66261-1-Ig (same clone as 66261-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66261-1-Ig (PAI-1 antibody at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 66261-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SERPINE1 antibody included
  • IHC staining of human kidney using 66261-1-Ig (same clone as 66261-1-PBS)

    IHC staining of human kidney using 66261-1-Ig (same clone as 66261-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 66261-1-Ig (PAI-1 antibody at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 66261-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with SERPINE1 antibody included
  • IF Staining of HepG2 using 66261-1-Ig (same clone as 66261-1-PBS)

    IF Staining of HepG2 using 66261-1-Ig (same clone as 66261-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HepG2 cells using PAI-1 antibody (66261-1-Ig, Clone: 1H4A5 ) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Mouse IgG(H+L). This data was developed using the same antibody clone with 66261-1-PBS in a different storage buffer formulation.

Serpin E1/PAI-1 Monoclonal antibody, PBS Only

Serpin E1/PAI-1 Monoclonal Antibody for WB, IHC, IF/ICC, Indirect ELISA
Cat No. 66261-1-PBS

产品说明书

CloneNo. 1H4A5

宿主/亚型

Mouse / IgG1

种属反应性

human, mouse, pig

应用

WB, IHC, IF/ICC, Indirect ELISA

别名

PAI-1, SERPINE1, SERPINE1, PAI-1, Plasminogen activator inhibitor 1, PAI1

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy SERPINE1 Ready-To-Use IHC Kit. SERPINE1 primary antibody included.

产品信息

66261-1-PBS targets Serpin E1/PAI-1 in WB, IHC, IF/ICC, Indirect ELISA applications and shows reactivity with human, mouse, pig samples.

经测试应用 WB, IHC, IF/ICC, Indirect ELISA Application Description
经测试反应性 human, mouse, pig
免疫原 Serpin E1/PAI-1 fusion protein Ag22411 种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
别名 PAI-1, SERPINE1, SERPINE1, PAI-1, Plasminogen activator inhibitor 1, PAI1
计算分子量 402 aa, 45 kDa
观测分子量45-50 kDa
GenBank蛋白编号BC010860
基因名称 PAI-1
Gene ID (NCBI) 5054
RRIDAB_2881648
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDP05121
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

SERPINE1, also named Plasminogen activator inhibitor type 1 (PAI-1), is a member of the serine protease inhibitor (SERPIN) superfamily. PAI-1 is the principal inhibitor of tissue plasminogen activator (tPA) and uPA, and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. The mature 379-residue protein had a calculated unglycosylated molecular mass of 42.7 kD. Three putative glycosylation sites were found.