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验证数据展示

  • Cytometric bead array standard curve of MP50408-4

    Cytometric bead array standard curve of MP50408-4

    Cytometric bead array standard curve of MP50408-4, PAX8 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60144-1-PBS. Detection antibody: 68979-2-PBS. Standard:Ag0306. Range: 0.781-100 ng/mL.

  • Cytometric bead array standard curve of MP50408-5

    Cytometric bead array standard curve of MP50408-5

    Cytometric bead array standard curve of MP50408-5, PAX8 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60144-1-PBS. Detection antibody: 68979-1-PBS. Standard:Ag0306. Range: 1.563-100 ng/mL.

PAX8 Monoclonal antibody, PBS Only (Capture)

PAX8 Monoclonal Antibody for Cytometric bead array, Indirect ELISA
Cat No. 60144-1-PBS

产品说明书

CloneNo. 1C5A11

宿主/亚型

Mouse / IgG2b

种属反应性

human

应用

Cytometric bead array, Indirect ELISA

别名

PAX-8, PAX 8, Paired box protein Pax-8, Paired box protein Pax 8, paired box 8

缓冲液配方:  PBS Only
PBS Only
偶联物:  Unconjugated
规格: 

-/ -

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Planning an IHC experiment? We recommend our IHCeasy PAX8 Ready-To-Use IHC Kit. PAX8 primary antibody included.

产品信息

60144-1-PBS targets PAX8 as part of a matched antibody pair:

MP50408-4: 60144-1-PBS capture and 68979-2-PBS detection (validated in Cytometric bead array)

MP50408-5: 60144-1-PBS capture and 68979-1-PBS detection (validated in Cytometric bead array)

Unconjugated mouse monoclonal antibody pair in PBS only (BSA and azide free) storage buffer at a concentration of 1 mg/mL, ready for conjugation.

This conjugation ready format makes antibodies ideal for use in many applications including: ELISAs, multiplex assays requiring matched pairs, mass cytometry, and multiplex imaging applications.Antibody use should be optimized by the end user for each application and assay.

经测试应用 Cytometric bead array, Indirect ELISA Application Description
经测试反应性 human
免疫原 PAX8 fusion protein Ag0306 种属同源性预测
宿主/亚型 Mouse / IgG2b
抗体类别 Monoclonal
产品类型 Antibody
全称 paired box 8
别名 PAX-8, PAX 8, Paired box protein Pax-8, Paired box protein Pax 8, paired box 8
计算分子量 48 kDa
GenBank蛋白编号BC001060
基因名称 PAX8
Gene ID (NCBI) 7849
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDQ06710
储存缓冲液 PBS Only
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PAX8 is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain and a paired-type homeodomain. It is expressed during organogenesis of the thyroid gland, kidney and Mullerian system. It is thought to regulate the expression of Wilms tumor suppressor (WT1) gene and mutations in PAX8 have been associated with Wilms tumor cells, thyroid and ovarian carcinomas. PAX8 is a useful marker in distinguishing ovarian carcinomas from mammary carcinomas (PMID: 18724243). PAX8 is expressed in a high percentage of ovarian serous, endometrioid, and clear cell carcinomas, but only rarely in primary ovarian mucinous adenocarcinomas.

PAX8 has 5 isoforms with calculated MW 31kd, 34kd, 41kd, 43kd and 48kd. And there is a 60kd band corresponding to the electrophoretic mobility of PAX8 (PMID:15650356).