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PCDHB10 Polyclonal antibody

PCDHB10 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 14785-1-AP

Print datasheet

Synonyms

PCDH beta 10, PCDH BETA10, PCDHB10, PCHB10, protocadherin beta 10

验证数据展示

  • IHC staining of human pancreas cancer using 14785-1-AP

    IHC staining of human pancreas cancer using 14785-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with PCDHB10 antibody included
  • IHC staining of human pancreas cancer using 14785-1-AP

    IHC staining of human pancreas cancer using 14785-1-AP

    Immunohistochemical analysis of paraffin-embedded human pancreas cancer tissue slide using 14785-1-AP (PCDHB10 antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

    Ready-to-use IHC kits available with PCDHB10 antibody included

经过测试的应用

Positive IHC detected inhuman pancreas cancer tissue, human gliomas tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Planning an IHC experiment? We recommend our IHCeasy PCDHB10 Ready-To-Use IHC Kit. PCDHB10 primary antibody included.

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:250-1:1000
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

14785-1-AP targets PCDHB10 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen PCDHB10 fusion protein Ag6427 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name protocadherin beta 10
Synonyms PCDH beta 10, PCDH BETA10, PCDHB10, PCHB10, protocadherin beta 10
Calculated Molecular Weight 88 kDa
GenBank Accession NumberBC031837
Gene Symbol PCDHB10
Gene ID (NCBI) 56126
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UN67
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). PCDHB10 belongs to the β-protocadherin (PCDHB) cluster. PCDHB cluster acts as a DNA methylation marker of aggressiveness in neuroblastoma (PMID: 26103900).

实验方案

Product Specific Protocols
IHC protocol for PCDHB10 antibody 14785-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols