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PCDHGC5 Polyclonal antibody

PCDHGC5 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 23848-1-AP

Print datasheet

Synonyms

验证数据展示

  • IHC staining of human lung cancer using 23848-1-AP

    IHC staining of human lung cancer using 23848-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

  • IHC staining of human lung cancer using 23848-1-AP

    IHC staining of human lung cancer using 23848-1-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 23848-1-AP (PCDHGC5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

经过测试的应用

Positive IHC detected inhuman lung cancer tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

23848-1-AP targets PCDHGC5 in IHC, ELISA applications and shows reactivity with human samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human
Immunogen PCDHGC5 fusion protein Ag20867 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name protocadherin gamma subfamily C, 5
Synonyms
Calculated Molecular Weight581aa,65 kDa; 944aa,102 kDa
GenBank Accession NumberBC112081
Gene Symbol PCDHGC5
Gene ID (NCBI) 56097
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen Affinity purified
UNIPROT IDQ9Y5F6
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Protocadherins, which constitute the largest subgroup within the cadherin superfamily, are predominantly expressed in the nervous system and are probably involved in the regulation of neuronal recognition and connectivity (PMID: 17936607; 12231349; 17133224). The protocadherin subfamily can be further subdivided into three groups: the clustered protocadherins, comprising α-, β- and γ-protocadherins; δ-protocadherins; and others, many of which are solitary (PMID: 17133224). Disruption of the γ-protocadherins locus causes neonatal lethality, and Pcdhgc3, Pcdhgc4, and Pcdhgc5 are essential for the observed lethality.

实验方案

Product Specific Protocols
IHC protocol for PCDHGC5 antibody 23848-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols