PCSK7 Polyclonal antibody
PCSK7 Polyclonal Antibody for WB, IHC, ELISA
Host / Isotype
Rabbit / IgG
Reactivity
human, mouse
Applications
WB, IHC, ELISA
Conjugate
Unconjugated
验证数据展示
经过测试的应用
Positive WB detected in | mouse spleen tissue, mouse thymus tissue |
Positive IHC detected in | human lymphoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释比
Application | Dilution |
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Western Blot (WB) | WB : 1:200-1:1000 |
Immunohistochemistry (IHC) | IHC : 1:50-1:500 |
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
Sample-dependent, Check data in validation data gallery. |
发表文章中的应用
IHC | See 1 publications below |
产品信息
12044-1-AP targets PCSK7 in WB, IHC, ELISA applications and shows reactivity with human, mouse samples.
Tested Applications | WB, IHC, ELISA Application Description |
Cited Applications | IHC |
Tested Reactivity | human, mouse |
Cited Reactivity | human |
Immunogen | PCSK7 fusion protein Ag2674 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | proprotein convertase subtilisin/kexin type 7 |
Synonyms | SPC7, PC8, PC7, LPC, hPC8 |
Calculated Molecular Weight | 785 aa, 86 kDa |
Observed Molecular Weight | 68 kDa |
GenBank Accession Number | BC010696 |
Gene Symbol | PCSK7 |
Gene ID (NCBI) | 9159 |
RRID | AB_2877820 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q16549 |
Storage Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
Storage Conditions | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PCSK7(Proprotein convertase subtilisin/kexin type 7) is also named as LPC, PC7, PC8, SPC7 and belongs to the peptidase S8 family. It has ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RXXX[KR]R consensus motif. The full length protein has 4 glycosylation sites and it can be N-glycosylated.
实验方案
Product Specific Protocols | |
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WB protocol for PCSK7 antibody 12044-1-AP | Download protocol |
IHC protocol for PCSK7 antibody 12044-1-AP | Download protocol |
Standard Protocols | |
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Click here to view our Standard Protocols |
发表文章
Species | Application | Title |
---|---|---|
Front Pharmacol Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease |