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PCYOX1 Polyclonal antibody

PCYOX1 Polyclonal Antibody for IHC, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

IHC, ELISA

Conjugate

Unconjugated

Cat no : 18868-1-AP

Print datasheet

Synonyms

KIAA0908, PCL1, PCYOX1, Prenylcysteine lyase, prenylcysteine oxidase 1

验证数据展示

  • IHC staining of human colon using 18868-1-AP

    IHC staining of human colon using 18868-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon using 18868-1-AP (PCYOX1 antibody) at dilution of 1:50 (under 10x lens).

  • IHC staining of human colon using 18868-1-AP

    IHC staining of human colon using 18868-1-AP

    Immunohistochemical analysis of paraffin-embedded human colon using 18868-1-AP (PCYOX1 antibody) at dilution of 1:50 (under 40x lens).

经过测试的应用

Positive IHC detected inhuman colon tissue
Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0

推荐稀释比

ApplicationDilution
Immunohistochemistry (IHC)IHC : 1:20-1:200
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

18868-1-AP targets PCYOX1 in IHC, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications IHC, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen PCYOX1 fusion protein Ag4316 种属同源性预测
Host / Isotype Rabbit / IgG
Class Polyclonal
Type Antibody
Full Name prenylcysteine oxidase 1
Synonyms KIAA0908, PCL1, PCYOX1, Prenylcysteine lyase, prenylcysteine oxidase 1
Calculated Molecular Weight 505 aa, 57 kDa
GenBank Accession NumberBC033815
Gene Symbol PCYOX1
Gene ID (NCBI) 51449
RRIDAB_10598471
Conjugate Unconjugated
Form Liquid
Purification MethodAntigen affinity purification
UNIPROT IDQ9UHG3
Storage Buffer PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Storage ConditionsStore at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

PCYOX1(Prenylcysteine oxidase 1) is also named as KIAA0908, PCL1, prenylcysteine lyase and belongs to the prenylcysteine oxidase family. The deduced 505-amino acid protein contains a predicted signal sequence, several transmembrane regions, and four potential N-glycosylation sites. It is a glycosylated enzyme involved in prenylated protein catabolism, releasing a free cysteine and a hydrophobic isoprenoid product. Immunofluorescence studies of PCYOX1 showed a nonnuclear punctate pattern, and PCYOX1 colocalized with lysosomal marker LAMP1 in HEK293 cells(PMID:10585463). The enzyme is isolated from bovine brain membranes and exhibits an apparent molecular mass of 63 kDa(PMID:9287348).

实验方案

Product Specific Protocols
IHC protocol for PCYOX1 antibody 18868-1-APDownload protocol
Standard Protocols
Click here to view our Standard Protocols