验证数据展示
产品信息
12587-1-PBS targets PDCD4 in WB, IHC, FC (Intra), IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
Tested Applications | WB, IHC, FC (Intra), IP, Indirect ELISA Application Description |
Tested Reactivity | human, mouse, rat |
Immunogen | PDCD4 fusion protein Ag3288 种属同源性预测 |
Host / Isotype | Rabbit / IgG |
Class | Polyclonal |
Type | Antibody |
Full Name | programmed cell death 4 (neoplastic transformation inhibitor) |
Synonyms | |
Calculated Molecular Weight | 469 aa, 52 kDa |
Observed Molecular Weight | 54-64 kDa |
GenBank Accession Number | BC026104 |
Gene Symbol | PDCD4 |
Gene ID (NCBI) | 27250 |
RRID | AB_2162296 |
Conjugate | Unconjugated |
Form | Liquid |
Purification Method | Antigen affinity purification |
UNIPROT ID | Q53EL6 |
Storage Buffer | PBS Only |
Storage Conditions | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
Programmed cell death 4 (Pdcd4) is a novel tumor suppressor that inhibits translation, progression and invasion. It was first identified as being differnetially upregulated during apoptosis. Pdcd4 interferes with the activity of the eukaryotic initiation factor (eIF) 4A by displacing the scaffold protein eIF4G from its binding to the RNA helicase eIF4A. The calculated molecular wight of unmodified PDCD4 protein is 52 kDa, but the modified protein is about 54-64 kDa.