验证数据展示
经过测试的应用
| Positive WB detected in | Y79 cells |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:200-1:1000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
55183-1-AP targets PDE6C in WB, ELISA applications and shows reactivity with human samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | Peptide 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| 别名 | cGMP phosphodiesterase 6C, PDE6C, PDEA2 |
| 计算分子量 | 99 kDa |
| 观测分子量 | 52 kDa, 99 kDa |
| GenBank蛋白编号 | NM_006204 |
| 基因名称 | PDE6C |
| Gene ID (NCBI) | 5146 |
| RRID | AB_10837359 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | P51160 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Aliquoting is unnecessary for -20oC storage. |
背景介绍
PDE6C, also named as PDEA2, belongs to the cyclic nucleotide phosphodiesterase family. It catalyze the reaction: Guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. Defects in PDE6C are the cause of cone dystrophy type 4 (COD4). Mutations in the PDE6C gene encoding the catalytic subunit of the cone photoreceptor phosphodiesterase as a cause of autosomal recessive achromatopsia.(PMID:19887631) This antibody is specific to PDE6C.
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PDE6C antibody 55183-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |