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PDE6D Monoclonal antibody, PBS Only

PDE6D Monoclonal Antibody for WB, IHC, ELISA

Host / Isotype

Mouse / IgG1

Reactivity

human, mouse, rat, pig

Applications

WB, IHC, ELISA

Conjugate

Unconjugated

CloneNo.

1H4B6

Cat no : 67565-1-PBS

Print datasheet

Synonyms

PDED, 1H4B6

验证数据展示

  • WB analysis of Jurkat using 67565-1-Ig (same clone as 67565-1-PBS)

    WB analysis of Jurkat using 67565-1-Ig (same clone as 67565-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67565-1-Ig (PDE6D antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

  • WB analysis using 67565-1-Ig (same clone as 67565-1-PBS)

    WB analysis using 67565-1-Ig (same clone as 67565-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67565-1-Ig (PDE6D antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

  • IHC staining of mouse brain using 67565-1-Ig (same clone as 67565-1-PBS)

    IHC staining of mouse brain using 67565-1-Ig (same clone as 67565-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 67565-1-Ig (PDE6D antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67565-1-PBS in a different storage buffer formulation.

产品信息

67565-1-PBS targets PDE6D in WB, IHC, ELISA applications and shows reactivity with human, mouse, rat, pig samples.

Tested Applications WB, IHC, ELISA Application Description
Tested Reactivity human, mouse, rat, pig
Immunogen PDE6D fusion protein Ag29563 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name phosphodiesterase 6D, cGMP-specific, rod, delta
Synonyms PDED, 1H4B6
Calculated Molecular Weight 17 KDa
Observed Molecular Weight 15-17 kDa
GenBank Accession NumberNM_002601
Gene Symbol PDE6D
Gene ID (NCBI) 5147
RRIDAB_2882779
Conjugate Unconjugated
Form Liquid
Purification MethodProtein G purification
UNIPROT IDO43924
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.