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  • Featured Product
  • KD/KO Validated

PDE6D Recombinant antibody, PBS Only

PDE6D Uni-rAbTM Recombinant Antibody for WB, ELISA

Host / Isotype

Rabbit / IgG

Reactivity

human, mouse, rat

Applications

WB, ELISA

Conjugate

Unconjugated

CloneNo.

230546H1

Cat no : 83503-1-PBS

Print datasheet

Synonyms

PDED, 230546H1

验证数据展示

  • WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

    WB analysis using 83503-1-RR (same clone as 83503-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83503-1-RR (PDE6D antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

    WB analysis of HeLa using 83503-1-RR (same clone as 83503-1-PBS)

    WB result of PDE6D antibody (83503-1-RR; 1:4000; incubated at room temperature for 1.5 hours) with sh-Control and sh-PDE6D transfected HeLa cells. This data was developed using the same antibody clone with 83503-1-PBS in a different storage buffer formulation.

产品信息

83503-1-PBS targets PDE6D in WB, ELISA applications and shows reactivity with human, mouse, rat samples.

Tested Applications WB, ELISA Application Description
Tested Reactivity human, mouse, rat
Immunogen PDE6D fusion protein Ag29563 种属同源性预测
Host / Isotype Rabbit / IgG
Class Recombinant
Type Antibody
Full Name phosphodiesterase 6D, cGMP-specific, rod, delta
Synonyms PDED, 230546H1
Calculated Molecular Weight 17 KDa
Observed Molecular Weight 14-17 kDa
GenBank Accession NumberNM_002601
Gene Symbol PDE6D
Gene ID (NCBI) 5147
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purfication
UNIPROT IDO43924
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PDE6D, also known as PDED, belongs to the PDE6D/unc-119 family. PDE6D is a ubiquitously expressed prenyl-binding protein. By binding to prenyl moieties, PDE6D mediates the shuttling of prenylated proteins between membranes. Thereby, it regulates the membrane association of Ras and Rap GTPases (PMID: 36672247). In addition, research has shown that PDE6D is overexpressed in liver cancer and correlated with tumor stages, grading, and ERK activation (PMID: 30901922). The calculated molecular weight of PDE6D is 17 kDa.