验证数据展示
产品信息
29593-1-PBS targets PDIR in WB, IHC, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, mouse, rat |
免疫原 | PDIR fusion protein Ag31479 种属同源性预测 |
宿主/亚型 | Rabbit / IgG |
抗体类别 | Polyclonal |
产品类型 | Antibody |
全称 | protein disulfide isomerase family A, member 5 |
别名 | |
计算分子量 | 60 kDa |
观测分子量 | 60 kDa |
GenBank蛋白编号 | BC001625 |
基因名称 | PDIR |
Gene ID (NCBI) | 10954 |
RRID | AB_2918329 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Antigen affinity purification |
UNIPROT ID | Q14554 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
PDIR(Protein disulfide isomerase-related protein), also known as PDIA5 (Protein Disulfide Isomerase Family A Member 5), is a member of the PDI gene family and also exhibits chaperone-like activity. PDIR protein is correlated with immune infiltration, which is highly expressed in glioma and participates in glioma progression(PMID: 33664747). PDIR contributes to disulfide bond rearrangement in ATF6α under stress conditions that necessary for ATF6α activation upon ER stress(PMID: 24636989).