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PER2 (isoform 1) Monoclonal antibody, PBS Only

PER2 (isoform 1) Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG1

Reactivity

Human

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2E6C3

Cat no : 67513-1-PBS

Print datasheet

Synonyms

FASPS, hPER2, KIAA0347, PER2, period homolog 2 (Drosophila)

验证数据展示

  • WB analysis using 67513-1-Ig (same clone as 67513-1-PBS)

    WB analysis using 67513-1-Ig (same clone as 67513-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67513-1-Ig (PER2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67513-1-PBS in a different storage buffer formulation.

Planning an IHC experiment? We recommend our IHCeasy PER2 Ready-To-Use IHC Kit. PER2 primary antibody included.

产品信息

67513-1-PBS targets PER2 (isoform 1) in WB, Indirect ELISA applications and shows reactivity with Human samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity Human
Immunogen PER2 (isoform 1) fusion protein Ag29489 种属同源性预测
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Full Name period homolog 2 (Drosophila)
Synonyms FASPS, hPER2, KIAA0347, PER2, period homolog 2 (Drosophila)
Calculated Molecular Weight 137 kDa
Observed Molecular Weight150~160 kDa
GenBank Accession NumberNM_022817
Gene Symbol PER2
Gene ID (NCBI) 8864
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDO15055
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PER2, also named as KIAA0347, is a component of the circadian clock mechanism which is essential for generating circadian rhythms. Defects in PER2 are a cause of familial advanced sleep-phase syndrome (FASPS) which is characterized by very early sleep onset and offset. There are two isoforms of PER2: isoform 1 has an expected molecular size of about 140 kDa, and 67513-1-Ig detected molecular weight of 150-160 kDa (PMID:16675517), while isoform 2, known as PER2S (a second splicing variant of the human PER2 gene), has a molecular weight of about 45 kDa (PMID:26347774).