验证数据展示
经过测试的应用
| Positive WB detected in | mouse kidney tissue |
推荐稀释比
| 应用 | 推荐稀释比 |
|---|---|
| Western Blot (WB) | WB : 1:1000-1:4000 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, Check data in validation data gallery. | |
产品信息
15481-1-AP targets PEX11A in WB, ELISA applications and shows reactivity with human, mouse samples.
| 经测试应用 | WB, ELISA Application Description |
| 经测试反应性 | human, mouse |
| 免疫原 | PEX11A fusion protein Ag7797 种属同源性预测 |
| 宿主/亚型 | Rabbit / IgG |
| 抗体类别 | Polyclonal |
| 产品类型 | Antibody |
| 全称 | peroxisomal biogenesis factor 11 alpha |
| 别名 | HsPEX11p, Peroxin 11A, PEX11, PEX11 ALPHA, PEX11A, PMP28, Protein PEX11 homolog alpha |
| 计算分子量 | 28 kDa |
| 观测分子量 | 28 kDa |
| GenBank蛋白编号 | BC009697 |
| 基因名称 | PEX11A |
| Gene ID (NCBI) | 8800 |
| RRID | AB_3085464 |
| 偶联类型 | Unconjugated |
| 形式 | Liquid |
| 纯化方式 | Antigen affinity purification |
| UNIPROT ID | O75192 |
| 储存缓冲液 | PBS with 0.02% sodium azide and 50% glycerol , pH 7.3 |
| 储存条件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. |
背景介绍
Peroxisomes are ubiquitous organelles bound by a single membrane. Peroxisomal biogenesis factor 11 alpha (PEX11A) is one of PEX11 gene family members involved in peroxisome elongation. PEX11A is highly expressed in the kidney and liver (PMID: 25113963). PEX11A deficiency will impaire peroxisome elongation, leading to the reduction of functional peroxisome, eventually leading to the reduction of fatty acid oxidation capacity and the formation of steatosis (PMID: 23169785; PMID: 25113963)
实验方案
| Product Specific Protocols | |
|---|---|
| WB protocol for PEX11A antibody 15481-1-AP | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |