验证数据展示
产品信息
66309-1-PBS targets PEX5 in WB, IHC, Indirect ELISA applications and shows reactivity with human, pig, rat samples.
经测试应用 | WB, IHC, Indirect ELISA Application Description |
经测试反应性 | human, pig, rat |
免疫原 | PEX5 fusion protein Ag3268 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | peroxisomal biogenesis factor 5 |
别名 | Cell and organelle markers, Peroxin 5, Peroxisome Marker, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1 |
计算分子量 | 631 aa, 70 kDa |
观测分子量 | 70-80 kDa |
GenBank蛋白编号 | BC010621 |
基因名称 | PEX5 |
Gene ID (NCBI) | 5830 |
RRID | AB_2881691 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | P50542 |
储存缓冲液 | PBS Only |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The peroxisomal targeting signal type1 (PTS1) receptor, PEX5, is one member of peroxins (PEXs) which are proteins required for peroxisome assembly. PEX5 and PEX7 function as receptors that recognize PTS1- and PTS2- containing proteins, respectively, and PEX5 binds PTS1 through its C-terminal 40-kDa tetratricopeptide repeat domain. It is a predominantly cytoplasmic, partly peroxisomal protein that appears to shuttle between these compartments as it mediates the import of PTS1-containing proteins. PEX5 has been reported to interact with PEX10, PEX12, PEX13, and PEX14. Defects in PEX5 are a cause of Zellweger syndrome (ZWS), which is a lethal peroxisome biogenesis disorder.