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PTGDS Monoclonal antibody, PBS Only

PTGDS Monoclonal Antibody for WB, Indirect ELISA

Host / Isotype

Mouse / IgG2a

Reactivity

human, mouse, rat, pig, rabbit

Applications

WB, Indirect ELISA

Conjugate

Unconjugated

CloneNo.

2D6E7

Cat no : 68783-3-PBS

Print datasheet

Synonyms

Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthase, EC:5.3.99.2, Cerebrin-28, Beta-trace protein

验证数据展示

  • WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

  • WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    WB analysis using 68783-3-Ig (same clone as 68783-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68783-3-Ig (PGDS antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68783-3-PBS in a different storage buffer formulation.

产品信息

68783-3-PBS targets PTGDS in WB, Indirect ELISA applications and shows reactivity with human, mouse, rat, pig, rabbit samples.

Tested Applications WB, Indirect ELISA Application Description
Tested Reactivity human, mouse, rat, pig, rabbit
Immunogen PTGDS fusion protein Ag34483 种属同源性预测
Host / Isotype Mouse / IgG2a
Class Monoclonal
Type Antibody
Full Name prostaglandin D2 synthase 21kDa (brain)
Synonyms Lipocalin-type prostaglandin-D synthase, Glutathione-independent PGD synthase, EC:5.3.99.2, Cerebrin-28, Beta-trace protein
Calculated Molecular Weight 21 kDa
Observed Molecular Weight 28 kDa
GenBank Accession NumberBC005939
Gene Symbol PTGDS
Gene ID (NCBI) 5730
Conjugate Unconjugated
Form Liquid
Purification MethodProtein A purification
UNIPROT IDP41222
Storage Buffer PBS Only
Storage ConditionsStore at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

Glycoprotein prostaglandin D2 synthase (PTGDS), also known as L-PGDS, PGDS, and LPGDS, is a member of the lipocalin superfamily and plays dual roles in prostaglandins metabolism and lipid transport (PMID: 34743203). PTGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PTGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. PTGDS is abundantly expressed in the brain and heart and has also been found in testis, prostate, kidney, spleen and leukocytes. It can be found as a collection of monomeric glycoforms with molecular weights in the 27-34 kDa range (PMID: 32430846).