验证数据展示
产品信息
68196-1-PBS targets PHF5A in WB, Indirect ELISA applications and shows reactivity with Human, mouse samples.
经测试应用 | WB, Indirect ELISA Application Description |
经测试反应性 | Human, mouse |
免疫原 | PHF5A fusion protein Ag7804 种属同源性预测 |
宿主/亚型 | Mouse / IgG1 |
抗体类别 | Monoclonal |
产品类型 | Antibody |
全称 | PHD finger protein 5A |
别名 | bK223H9.2, INI, PHD finger protein 5A, PHF5A, SF3b14b |
计算分子量 | 12 kDa |
观测分子量 | 12 kDa |
GenBank蛋白编号 | BC007321 |
基因名称 | PHF5A |
Gene ID (NCBI) | 84844 |
偶联类型 | Unconjugated |
形式 | Liquid |
纯化方式 | Protein G purification |
UNIPROT ID | Q7RTV0 |
储存缓冲液 | PBS only , pH 7.3 |
储存条件 | Store at -80°C. The product is shipped with ice packs. Upon receipt, store it immediately at -80°C |
背景介绍
The PHD finger-like domain protein 5a (PHF5A) is ubiquitously expressed and is located in the nucleus. The gene Phf5a and its human counterpart PHF5A (former name Ini) are located on rat chromosome 7 (RNO7q34) and human chromosome 22 (HSA2213q2), respectively. The rat gene consists of four exons, while the human gene have five exons. Both genes encode a highly conserved protein of 110 amino acids that contains a PHD finger domain.(PMID: 23675859) It acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha and is involved in pre-mRNA splicing.