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PHGDH Recombinant antibody, PBS Only

PHGDH Uni-rAbTM Recombinant Antibody for WB, IHC, IP, Indirect ELISA
Cat No. 81986-1-PBS

产品说明书

CloneNo. 5L16

宿主/亚型

Rabbit / IgG

种属反应性

human, mouse, rat

应用

WB, IHC, IP, Indirect ELISA

EC:1.1.1.37, D-3-phosphoglycerate dehydrogenase, 5L16, 3-PGDH, 3PGDH

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格: 

-/ -


Planning an IHC experiment? We recommend our IHCeasy PHGDH Ready-To-Use IHC Kit. PHGDH primary antibody included.

产品信息

81986-1-PBS targets PHGDH in WB, IHC, IP, Indirect ELISA applications and shows reactivity with human, mouse, rat samples.

经测试应用 WB, IHC, IP, Indirect ELISA Application Description
经测试反应性 human, mouse, rat
免疫原 PHGDH fusion protein Ag6445 种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Recombinant
产品类型 Antibody
全称 phosphoglycerate dehydrogenase
别名 EC:1.1.1.37, D-3-phosphoglycerate dehydrogenase, 5L16, 3-PGDH, 3PGDH
计算分子量 57 kDa
观测分子量 57 kDa
GenBank蛋白编号BC000303
基因名称 PHGDH
Gene ID (NCBI) 26227
偶联类型 Unconjugated
形式 Liquid
纯化方式Protein A purification
UNIPROT IDO43175
储存缓冲液 PBS only , pH 7.3
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PHGDH(D-3-phosphoglycerate dehydrogenase) is also named as 3-PGDH, PGDH3 and belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. It catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. 3-PGDH deficiency is a rare recessive inborn error in the biosynthesis of the amino acid L-serine characterized clinically by congenital microcephaly, psychomotor retardation, and intractable seizures(PMID:19235232 ).

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